PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G46870.1
Common NameF19D11.25, NGA1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family B3
Protein Properties Length: 310aa    MW: 34889.6 Da    PI: 6.7472
Description B3 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G46870.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B3100.69.1e-3235140199
                  EEEE-..-HHHHTT-EE--HHH.HTT....---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-.SS..SEE. CS
           B3   1 ffkvltpsdvlksgrlvlpkkfaeeh....ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkld.gr..sefe 91 
                  f+kv tpsdv+k++rlv+pk++ae++    ++++e++  l +ed++g+sW+++++y+++s++yv+tkGW++Fvk+++L++gD+v F++  g+  ++ +
  AT2G46870.1  35 FDKVVTPSDVGKLNRLVIPKQHAERFfpldSSSNEKGLLLNFEDLTGKSWRFRYSYWNSSQSYVMTKGWSRFVKDKKLDAGDIVSFQRCvGDsgRDSR 132
                  89****************************66677899*************************************************44333246777 PP

                  .EEEEE-S CS
           B3  92 lvvkvfrk 99 
                  l++ ++r+
  AT2G46870.1 133 LFIDWRRR 140
                  88888876 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.103.5E-4125142IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019363.92E-3031127IPR015300DNA-binding pseudobarrel domain
CDDcd100174.57E-2533135No hitNo description
SMARTSM010199.5E-2335141IPR003340B3 DNA binding domain
PROSITE profilePS5086314.74835141IPR003340B3 DNA binding domain
PfamPF023625.8E-2935140IPR003340B3 DNA binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009908Biological Processflower development
GO:0048366Biological Processleaf development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0025022anatomycollective leaf structure
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 310 aa     Download sequence    Send to blast
MMTDLSLTRD EDEEEAKPLA EEEGAREVAD REHMFDKVVT PSDVGKLNRL VIPKQHAERF  60
FPLDSSSNEK GLLLNFEDLT GKSWRFRYSY WNSSQSYVMT KGWSRFVKDK KLDAGDIVSF  120
QRCVGDSGRD SRLFIDWRRR PKVPDHPHFA AGAMFPRFYS FPSTNYSLYN HQQQRHHHSG  180
GGYNYHQIPR EFGYGYFVRS VDQRNNPAAA VADPLVIESV PVMMHGRANQ ELVGTAGKRL  240
RLFGVDMECG ESGMTNSTEE ESSSSGGSLP RGGGGGASSS SFFQLRLGSS SEDDHFTKKG  300
KSSLSFDLDQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wid_A1e-473214011117DNA-binding protein RAV1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.364410.0seed| vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible266760_at0.0
Expression AtlasAT2G46870-
AtGenExpressAT2G46870-
ATTED-IIAT2G46870-
Functional Description ? help Back to Top
Source Description
UniProtRegulates lateral organ growth. Functionally redundant with NGA2, NGA3 and NGA4. {ECO:0000269|PubMed:16603651}.
Function -- GeneRIF ? help Back to Top
  1. Data indicate that transcription factors TCP-NGA regulatory interaction is likely conserved in angiosperms, including important crop species.
    [PMID: 25625546]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G46870.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT3G58780(A)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDauxin
Interaction ? help Back to Top
Source Intact With
IntActSearch O82799
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G46870
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0044110.0AC004411.3 Arabidopsis thaliana chromosome 2 clone F14M4 map CIC06C03, complete sequence.
GenBankAC0053100.0AC005310.3 Arabidopsis thaliana chromosome 2 clone F19D11 map CIC06C03, complete sequence.
GenBankAK1180450.0AK118045.1 Arabidopsis thaliana At2g46870 mRNA for putative RAV-like B3 domain DNA binding protein, complete cds, clone: RAFL19-27-L04.
GenBankBT0085340.0BT008534.1 Arabidopsis thaliana clone U50690 putative RAV B3 domain DNA binding protein (At2g46870) mRNA, complete cds.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_566089.10.0B3 domain-containing transcription factor NGA1
SwissprotO827990.0NGA1_ARATH; B3 domain-containing transcription factor NGA1
TrEMBLC3VMM20.0C3VMM2_ARATH; NGATHA1
STRINGAT2G46870.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM13072899
Representative plantOGRP36516108
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Seki M, et al.
    Functional annotation of a full-length Arabidopsis cDNA collection.
    Science, 2002. 296(5565): p. 141-5
    [PMID:11910074]
  3. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  4. Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
    Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
    Plant J., 2004. 38(2): p. 366-79
    [PMID:15078338]
  5. De Paepe A,Vuylsteke M,Van Hummelen P,Zabeau M,Van Der Straeten D
    Transcriptional profiling by cDNA-AFLP and microarray analysis reveals novel insights into the early response to ethylene in Arabidopsis.
    Plant J., 2004. 39(4): p. 537-59
    [PMID:15272873]
  6. Alvarez JP, et al.
    Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and localized regulation of multiple targets in diverse species.
    Plant Cell, 2006. 18(5): p. 1134-51
    [PMID:16603651]
  7. Swaminathan K,Peterson K,Jack T
    The plant B3 superfamily.
    Trends Plant Sci., 2008. 13(12): p. 647-55
    [PMID:18986826]
  8. Ikeda M,Ohme-Takagi M
    A novel group of transcriptional repressors in Arabidopsis.
    Plant Cell Physiol., 2009. 50(5): p. 970-5
    [PMID:19324928]
  9. Alvarez JP,Goldshmidt A,Efroni I,Bowman JL,Eshed Y
    The NGATHA distal organ development genes are essential for style specification in Arabidopsis.
    Plant Cell, 2009. 21(5): p. 1373-93
    [PMID:19435933]
  10. Scacchi E, et al.
    Dynamic, auxin-responsive plasma membrane-to-nucleus movement of Arabidopsis BRX.
    Development, 2009. 136(12): p. 2059-67
    [PMID:19465596]
  11. Kwon SH, et al.
    Overexpression of a Brassica rapa NGATHA gene in Arabidopsis thaliana negatively affects cell proliferation during lateral organ and root growth.
    Plant Cell Physiol., 2009. 50(12): p. 2162-73
    [PMID:19880400]
  12. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  13. Ballester P,Navarrete-G
    Leaf expansion in Arabidopsis is controlled by a TCP-NGA regulatory module likely conserved in distantly related species.
    Physiol Plant, 2015. 155(1): p. 21-32
    [PMID:25625546]
  14. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]